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Consistent with known functions of the GSTs, several differentially regulated pathways and processes were associated with lipid metabolism and with the oxidative stress response, while additional interesting associations suggested altered cell cycle regulation and differences in apoptosis, cell invasion and migration

Chen, J., Hall, S

GSH depletion does not induce mitochondrial superoxide or alter mitochondrial mass in RPE cells It has been suggested that mitochondria are predominant source of ROS upon H 2 O 2 -induced oxidative stress 7

Adapter indices were ligated using the Nextera XT Index Kit (15055289, Illumina), and libraries were amplified using NEBNext High-Fidelity 2X PCR Master Mix (M0541S, NEB)